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[158, 159] demonstrated that B-CQDs and cobalt-conjugated N-CQDs elicited no detectable oxidative stress, apoptotic signalling, or microglial activation within neuronal tissues [158, 159]

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[DOI] [PubMed] [Google Scholar] 37.Futakuchi A., Morimoto T., Ikeda Y., Tanihara H., Inoue T., ROCK-S study group collaborators 2020 Intraocular pressure-lowering effects of ripasudil in uveitic glaucoma, exfoliation glaucoma, and steroid-induced glaucoma patients: ROCK-S, a multicentre historical cohort study

Lack of FDA Approval and Regulation One of the most pressing issues with BPC-157 is its lack of approval by the Food and Drug Administration (FDA)