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So most of the evidence comes from animal models , experiments on animals, most often rats

In a mouse model of inflammation, the decrease of LPS-induced paw edema by DATS was associated with reduced serum concentrations of the pro-inflammatory cytokines, TNF-, IL-6, and monocyte chemotactic protein-1 (MCP-1) (36)

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Bradycardia, increased cardiac output, and reversal of pulmonary hypertension in altitude natives living at sea level