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The permeabilization of the MOM due to MPT releases apoptogenic proteins such as cytochrome c, second mitochondria-derived activator of caspase (Smac), apoptosis inducing factor (AIF), and endonuclease G from the intermembrane space

The rats were allowed at least four days to recover from surgery before use

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The primary practical advantage of the blend format is compliance and consistency: a single reconstitution ensures both peptides are delivered in the intended ratio at every administration, eliminating the variability that arises from drawing from two separate vials