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Vegetarians and vegans: As B12 is primarily found in animal products, strict plant-based diets can increase the risk of deficiency

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Alcohol directly counteracts all of these processes by increasing inflammation, disrupting sleep, and stressing the bodys systems

Some research protocols account for this by using comparatively lower dosing ranges in female study cohorts, reflecting a generally increased sensitivity to IGF-1 receptor activation a pattern also documented in broader growth hormone axis research, not unique to IGF-1 LR3 specifically