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Annu Rev Pharmacol Toxicol 45, 51-88 (2005)
Possible Side Effects Observed in Research & Experimental Settings Glutathione has been explored in laboratory and experimental research settings, and observations in some research contexts have included: Administration-site irritation Temporary redness or discomfort Headache-related observations Nausea-related observations Fatigue- or lethargy-related observations Dizziness-related observations Gastrointestinal-discomfortrelated observations Temporary flushing or warmth-related sensations Responses may vary depending on experimental conditions, research amount, administration frequency, and experimental protocol design
Long-term use at physiological or modestly supraphysiological doses hasn't raised safety concerns in the existing literature
The hearts and kidneys were collected, frozen in isopentane at 30 C on dry ice, and stored at 80 C until studied
