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Note on visceral (smooth-muscle) cramps: Cramping sensations in the abdomen or chest (e.g., oesophageal spasm) or gut are typically due to visceral smooth-muscle activity or underlying organ pathology (e.g., colic, biliary colic, bowel obstruction, oesophageal spasm) and should be evaluated differently from skeletal muscle cramps

Perimenopause and menopause alter hormone levels in ways that favor weight gain

In addition to allergens, viruses, bacteria, and fungi also activate mast cells.[ref] Mast cells are also the primary source of histamine released to circulate in the body.[ref] The release of large amounts of histamine from mast cells can exacerbate problems with histamine from foods

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