Specifically, P-SF3B1 contacts the ISL of U6 snRNA, which may help to stabilize the U2/U6 snRNA catalytic core
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Although the mechanisms by which these reagents modulate GPx1 expression are not clear, it has been shown that GPx1 can be upregulated by activation of the peroxisome proliferator-activated receptor--coactivator-1a (PGC1) pathway, possibly via the subsequent activation of Nrf2 [161]
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