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These include:[ref] Inflammatory cytokines (IL-1B, IL-33), which cause the release of IL-6, TNF, IL-8, and VEGF Heavy metals (aluminum, cadmium, mercury) Herbicides (atrazine, glyphosate) Pathogens (Lyme disease, lipopolysaccharides from bacteria, certain viruses, and mold spores) These triggers can cause a two-phase reaction : Immediately released mediators include histamine, TNF, tryptase, RANKL, and serotonin

The risks of using this steroid on the scalp are negligible but we would not recommend use on the central face, beard area, or eyebrows

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Brain Res 815:8188 Liddell JR, Dringen R, Crack PJ, Robinson SR (2006a) Glutathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes