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It is a quaternary ammonium compound that the body synthesizes from the amino acids lysine and methionine, primarily in the liver, kidneys, and brain

One of the nuclear receptors, REV-ERB, is also a negative regulator of the rhythmic CLOCK transcription circuit

Key functions of CoQ10 include: Energy production in mitochondria Antioxidant protection against oxidative stress Cellular membrane stabilisation Involvement in cellular signalling Whilst CoQ10 supplements are widely available over the counter as food supplements (not licensed medicines), understanding their effects on major organs, particularly the kidneys and liver, is important for informed use

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