The TCF7L2 Gene: The Most Important Diabetes Gene You've Never Heard Of What it does to your GLP-1 system In 2006, scientists discovered that a variant in TCF7L2 was the strongest genetic risk factor for type 2 diabetes ever found in large population studies confirmed in hundreds of studies across multiple ethnicities, including South Asians
Charlotte Gurr Further reading Prostate cancer and MS drugs approved by NICE This week, NICE also recommended talazoparib (Talzenna, Pfizer), alongside enzalutamide (Xtandi
Further studies in rats found that GLP-1 agonists reduced the amount of dopamine released following alcohol consumption and relapse-type behaviors
Rienks M, Carai P, van Teeffelen J, Eskens B, Verhesen W, Hemmeryckx B, Johnson DM, van Leeuwen R, Jones EA, Heymans S, Papageorgiou AP