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Mechanism of Action: PT-141 binds to melanocortin receptors (MC3-R and MC4-R) in the hypothalamus in the brain

doi: 10.1016/j.pmpp.2016.01.003 45 LeeH.RaskinI

Psychiatry Res (2010) 181:13640.10.1016/j.pscychresns.2009.08.006 137 HulvershornLAKarneHGunnADHartwickSLWangYHummerTAet alNeural activation during facial emotion processing in unmedicated bipolar depression, euthymia, and mania