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Unlike antibodies or peptides, aptamers can be synthesized and modified with relative ease, have excellent stability, and avoid issues such as immunogenicity, making them appealing candidates for clinical translation ( We hypothesized that a fibrin-targeted, ROS-responsive GO nanocomposite encapsulating GSH (GO@GSH-FA) would selectively accumulate in ischemic brain regions and release its antioxidant payload in response to local oxidative stress

(2017) investigated AOD9604 in a preclinical model of joint pathology

Two genes encode distinct glutamate decarboxylases