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The appetite decrease is of course part of the intended mechanism, but it can become excessive during aggressive titration, leading to inadequate caloric and protein intake

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Sci Rep 7:45389 Mulholland CV, Lee BS, Chong A, Cui J, Pethe K, Berney M (2025) The mycobacterial ATP burst is a lysis artifact and serves as an assay for drug-induced cell wall damage