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Furthermore, compared with GLP-1 and Semaglutide SR18 exhibits stable interactions with GLP-1R over 1 s of molecular dynamics (MD) simulations, with appreciable binding affinity and energy, supporting its viability as a potential alternative to the current long-chain GLP-1R peptide agonists

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10.1016/j.diabres.2015.10.014 71 ShahbaziM.QudsiyaZ.FahelA.AminiA.TanoliT

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