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Journal of Diabetes Research, 25(6), 234-240
However, significant results typically appear after 12 weeks or more, especially when the injection is taken with a reduced-calorie diet plan and regular exercise as directed by a doctor
This comparative perspective juxtaposes the two compounds with respect to molecular pharmacology, clinical efficacy, safety, and potential clinical positioning, and proposes that, because resmetirom primarily targets hepatic lipid disposal whereas semaglutide unloads systemic caloric pressure, their complementary actions could be harnessed sequentially or in combination to achieve broader, more durable disease modification across the heterogeneous spectrum of patients with MASH
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