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Most importantly, it has not been tested in humans, so while the findings are intriguing, there is no evidence yet that it actually works
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MOTS-c activates AMPK (AMP-activated protein kinase), the master metabolic switch that signals cells to increase glucose uptake, accelerate fat oxidation, and promote mitochondrial biogenesis
Bringing together instructors and students of varying experience, Lefkovits remembers 'The EMBO course fascinated me so much that I became a renegade of molecular biology and instead of bacteria I switched to immunology' (Lefkovits 2025)
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