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Enzyme inactivation is not the only mechanism by which reactive electrophilic analogues of glutathione, such as EdAG, can elicit, disturb or disrupt biological mechanisms

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One study found that after just 30 days of supplementing, the group with low GSH levels saw improvements in VO2max, time trial, and Wingate test by 13.6%, 15.4%, and 11.4%, respectively

In addition, mature myeloid immune cells display altered phenotypes and functions with elevated production of proinflammatory cytokines such as TNF- and IL-6, which are closely related to age-related senescent inflammation, termed senoinflammation