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In summary, GLP-1RAs have the potential to inhibit neuroinflammation and promote nerve regeneration through the "Tregs-microglia-neuron/NPCs" axis: (1) GLP-1RAs directly and indirectly inhibit the activation of microglia, promote their M2 polarization, and secrete cytokines such as IL-4, IL-10, TGF - , IL-2 to exert anti-inflammatory effects (100)

Brain: Increased risk of stroke

Another reasonable scenario involves patients who experience a pronounced rollercoaster effect, severe symptoms for the first 48-72 hours followed by complete loss of appetite suppression by day six or seven

Screening is where we ask the right questions