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We have therefore established a link between a metabolic switch in response to GSH loss to the inability to mount antibody-mediated immune responses in vivo

They stimulate mucus secretion, enhancing the protective mucosal layer, and support the structural integrity and functional maintenance of the mucosal barrier (155)

Triple receptor agonists have the potential to further bridge the efficacy gap in WL between BS and the currently approved obesity pharmacotherapies, with the added potential for other synergistic metabolic benefits, such as improving glycaemia in people with T2D, and treating or preventing MASLD/MASH

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