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This dual mechanism is why the SURPASS and SURMOUNT clinical trials showed unprecedented results

doi:10.36849/JDD.6550 Samantha Ouellette BA, Giulia Frias BA, Radhika Shah MD PharmD, Mahin Alamgir MD, Cindy Wassef MD Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Somerset, NJ Abstract Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of antidiabetic agents that work by inducing insulin secretion and inhibiting release of glucagon in a glucose-dependent manner

Efficacy and safety of tirzepatide added to basal insulin in patients with type 2 diabetes in China (SURPASS-CN-INS)

It depends on your unique needs, goals, and body chemistry