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This alteration is accompanied by a metabolic change from glycolysis to a more oxidative form given by a decrease in phosphoglycerate mutase 1 (PGAM1), ALDOA, LDHA/B, and an increase in succinate dehydrogenase (SDH) A/B/C/D from the ADP-forming beta subunit of succinate-CoA ligase (SUCLA2), aconitase 2 (ACO2), PDK, and pyruvate dehydrogenase phosphatase (PDP), among others

Kim D, Cha J (2023) Association between medical complications according to continuity of care and medication adherence in patients with hypertension in Korea: a national population-based cohort study

Improvement with bupropion or a stimulant may suggest inadequate dopamine/norepinephrine signaling

To comply: ensure your lab facility has a sufficient number and adequately equipped facilities for all studies, including animal care, storage, and handling test and control articles, storage of test and control article mixtures, and performance of required routine and specialized procedures