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Zou found that peroxisomes promoted lipid peroxidation by synthesizing polyunsaturated ether phospholipids (PUFA-ePLs), which acted as substrates for lipid peroxidation, leading to ferroptosis [77]

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In conditions such as pancreatic ductal adenocarcinoma and heart failure, the effects caused by changes in lactate levels cannot be reversed merely by manipulating P300 [33, 41]

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