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We modified HCT116 dTAG SNIP1 cells by stable integration of flag-tagged SNIP1 ( F-SNIP1 ) gene into flp-in site

In the human brain, an increased total NAD + /NADH correlated with increased ATP levels and increased membrane phospholipid turnover (Cuenoud et al., 2020), as an oxidized cytoplasmic [NAD + ]/[NADH] likely directs glycerol-3-phosphate toward phospholipid synthesis to replace oxidized phospholipids to prevent ferroptosis instead of toward the G3PS