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[DOI] [PMC free article] [PubMed] [Google Scholar] 170.Amir I., Konikoff F.M., Oppenheim M., Gophna U., Half E.E

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Nicotine has been proven to be responsible for up-regulation of heme oxygenase-1 (HO-1) expression in human gingival fibroblasts (Vile and Tyrrell, 1993)