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According to previous studies, liraglutide attenuates myocardial hypertrophy and fibrosis following angiotensin II infusion by suppressing TGF-1/Smads signaling pathways [49]

They cannot be used to predict what will happen at microdose levels, where no comparable trial data exists

The SELECT trial (published in NEJM 2023) established semaglutide's cardiovascular benefits in patients with established cardiovascular disease and overweight or obesity but without diabetes