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Thus, not only the size but also the charge and shape of the glutathionylated substrate are relevant with GS in GSSG being the optimal leaving group in accordance with a 2nd glutathione-interaction site (Fig

Current areas of scientific investigation include oxidative stress research, cellular antioxidant studies, redox biology investigations, cellular defense mechanism research, metabolic pathway analysis, mitochondrial function studies, aging and longevity research, and cellular signaling investigations

Beyond its role as a direct antioxidant, glutathione is the primary agent in Phase II liver detoxification, a critical process for clearing harmful substances from the body