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Stay at the lowest effective dose if 1mg achieves clinical targets, there is no cost reason to titrate to 2mg

How GLP-1 receptor agonists work Understanding how GLP-1 compounds function helps researchers design better protocols and interpret results more accurately

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Nevertheless, some of the phase 3 trials investigating the glucose-lowering effects of dulaglutide also report significant weight loss: The AWARD-11 trial reported 5.2% (11lb) weight loss from baseline at 52 weeks, at the highest dulaglutide dose of 4.5mg/weekly [18]