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By adding L-theanine to the drinking water of cirrhotic rats established by carbon tetrachloride, it was found that L-theanine inhibited the expression of NF-B, downregulated the pro-inflammatory cytokines (e.g., IL-1 and IL-6), and profibrotic mediators (e.g., transforming growth factor and connective tissue growth factor), and promoted the expression of anti-inflammatory cytokine IL-10 and fibrinolytic enzyme metalloproteinases-13 (85)
Supports healthy skin and reversed signs of aging
However, the mechanisms underlying this association are not yet fully understood, and other factors such as genetics and environmental triggers may also play a role
10.1016/j.jmb.2019.03.006 3 AlexopoulosG
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