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Standard initial therapy for patients without neurological involvement is 1000 mcg intramuscularly (i.m.) three times a week for 2 weeks

For heart rate measurements, a surface ECG was recorded using custom-made needle electrodes placed on each limb

doi: 10.3389/fendo.2025.1630164 Received 17 May 2025 Accepted 09 July 2025 Published 28 July 2025 Volume 16 - 2025 Edited by Nazli Akin, Vrije University Brussels, Brussels, Belgium Reviewed by Yuan Gao, Gansu Agricultural University, Lanzhou, China Hong-Thuy Bui, International University, Vietnam Updates Copyright 2025 Zhong, Lu, Zhou, Ma, Li, Hu, Wan and Lu

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