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In cases of mild melanogenesis and non-pigmented forms, it is necessary to use a set of clinical and morphological criteria (localization, rate, and form of tumor growth), histological features (the combined directions of differentiation, correspondence between the cell type and their growth, the presence of appositional growth), detection of premelanin, and/or IHC study [37]

However, if you experience any digestive sensitivity, taking it with a small meal is a perfectly fine alternative

Patient Counseling Information Advise the patient to read the FDA-approved patient labeling (Medication Guide and Instructions for Use)

Kaklamanos et al., 2021