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More GLP-1 was needed to have the same biological effect, meaning they were resistant to GLP-1. Seeking confirmation The results were so surprising, Gloyns team spent the next several years confirming them

[4] [5] However, these studies predominantly involved populations with pre-diabetes or metabolic syndrome, and results may not generalise to individuals seeking weight loss without metabolic dysfunction

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If the pen was in a hot car, on a sunny windowsill, or in a room without air conditioning during summer, the situation is more concerning