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The results showed that M1 macrophages and CD8+ T cells were significantly increased in RA tissues compared to normal tissues, while M2 macrophages, resting mast cells, and dendritic cells were decreased, indicating substantial alterations in the RA immune microenvironment characterized by increased pro-inflammatory and decreased anti-inflammatory cells, potentially contributing to persistent inflammation

Low-dose aspirin upregulates tyrosine hydroxylase and increases dopamine production in dopaminergic neurons: implications for Parkinson's disease