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Ferroptosis, in turn, exacerbates inflammation by releasing oxidized byproducts and iron ions, thereby establishing a detrimental feedback loop involving immunity, metabolism, and ferroptosis within the OA microenvironment (105)

The overall prevalence of NASH is uncertain, as it relies on third-level referral centers with availability of liver biopsies, and is estimated between 1.5 and 6.45% (34)

Gene 67:3140 Editor information Editors and Affiliations Rights and permissions Copyright information 2019 Springer Science+Business Media, LLC, part of Springer Nature About this protocol Cite this protocol Kim, SY., Hakoshima, T

H., & Suher, M