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AOD9604 and Cartilage Biology Research In a collagenase-induced knee osteoarthritis rabbit model, intra-articular injection of AOD9604 significantly enhanced cartilage regeneration compared to saline controls, with combined AOD9604 and hyaluronic acid injections proving more effective than either treatment alone producing superior morphological and histopathological scores and a significantly shorter lameness period in the AOD9604 + HA group

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Most recently, researchers in Pomona, California, found significant improvements in cognitive function in a mouse model of Angelman Syndrome, a genetic disorder which, amongst other abnormalities, presents as severe deficits in both motor and cognitive functions