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Therefore, cancer cells may be more susceptible to ALT activation due to the binding of epitalon to the already reduced levels of histone H1, whereas normal cells may be more resilient as they naturally express higher levels of H1

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Sublingual B12, which bypasses the gastrointestinal tract, is the least invasive and potentially most cost-effective option, especially for individuals with impaired absorption, making it an attractive alternative for long-term and patient-friendly management (Vidal-Alaball et al., 2006)