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Mito-TEMPO, a mitochondrion-targeted antioxidant, significantly rescued doxorubicin (DOX)-induced myocardial ferroptosis, substantiated that mitochondrial oxidative damage underlies ferroptosis-induced cardiac injury [57]

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Liu Y, Lu S, Wu Llei, Yang L, Yang L, Wang J

Mechanistic Research Perspective Activation of growth hormonereleasing hormone receptor signaling Selective stimulation of ghrelin receptor (GHS-R) pathways Investigation of coordinated peptidereceptor signaling networks Analysis of downstream protein synthesis pathways Evaluation of metabolic and cellular growth signaling responses Primary Research Applications Growth Hormone Pathway Studies: Used in experimental models to analyze endocrine signaling mechanisms that regulate growth hormone release and receptor interactions