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References Soles BS, Wilson A, Lucas DR, Heider A (2018) Melanotic neuroectodermal tumor of infancy

The major difference is that with MCAS and mast cell activation disorder, a persons mast cells secrete many mediators of inflammation, such as leukotrienes and prostaglandins, not just histamine-although histamine is an important component

A secondary significant limitation is the pronounced variability in host microbiome composition and clinical responses to identical probiotic interventions