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These findings align with those of pooled analyses from liraglutide phase 2/3 trials in obesity171 and retrospective case-control studies in T2DM.172 It should be noted, however, that patients in the latter study did not receive high-dose GLP-1RAs approved for obesity and that detecting mental health disorders in routine clinical practice remains challenging

Degraded medication can cause unexpected muscle pain , headaches , fatigue , or increased gastrointestinal issues that might be attributed to the medication itself rather than to degradation