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In this study, our genetic screening of the previously constructed hairpin RNA-based Arabidopsis library 19 identified a glutathione (GSH)-deficient mutant that highly accumulated Glu, the previously defined molecule crucial for activation of plant defense, but disharmoniously exhibited attenuation of defense signaling events

Liedschulte V, Wachter A, Zhigang A, Rausch T: Exploiting plants for glutathione (GSH) production: uncoupling GSH synthesis from cellular controls results in unprecedented GSH accumulation

Some people wonder about splitting the dose into twice-weekly injections to flatten this curve