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Most compounds specifically targeting cancer NADPH metabolism are in preclinical studies, thus there are still challenges to address before these compounds enter the clinic
Cancer cells were rendered more susceptible to proapoptotic agents such as celecoxib, etoposide, and TRAIL when WA activated the ETS-like transcription factor 1/C-EBP identical protein pathway and the extracellular signal-regulated kinase (ERK) ribosomal S6 kinase signalling pathway, leading to the expression of death receptor 5
Diabetes Complications 29 , 670674 (2015)
10.1016/j.canlet.2013.09.009 132 MoussaL.DemarquayC.RthorG.BenadjaoudM
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