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The second is a TGN-independent pathway, suggesting that it is different from the secretion pathway of most proteins

Both imitate GLP-1, a hormone the gut releases after eating

According to the Cleveland Clinic GLP-1 Agonists overview, these drugs are usually given via subcutaneous injections and work best when paired with healthy lifestyle changes

HEK-Blue GLP-1 cells express approximately 1,000 GLP-1 receptors per cell, a surface receptor density consistent with physiological levels reported in the literature [1,2]