It is to note that reference [19] provides further details on this calculation method
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In the IMPACT trial, pemvidutide achieved mean weight losses of 4.8% and 5.8% with 1.2 and 1.8 mg doses respectively at 24 weeks, compared to 0.5% with placebo, with weight loss curves showing no evidence of plateauing, suggesting continued benefit with longer treatment [49-51]
Gastrointestinal Side Effects GLP-1 agonists often cause gastrointestinal side effects, such as nausea, vomiting, and diarrhea, especially when first starting the medication