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Together, they address both structural (fibrosis, neuronal damage) and functional (inflammation, oxidative stress) aspects of disease

The neuropeptide calcitonin gene-related peptide stimulates insulin-like growth factor I production by primary fetal rat osteoblasts

The same analysis for TXNIP showed the opposite pattern, characterized by a significant increase in weak staining intensity in both the ileum and colon of metformin-treated mice, indicating downregulation of TXNIP (Fig

Currently, two once-weekly GLP-1RA-based therapies are available for antiobesity treatment (semaglutide (Wegovy) and tirzepatide (Zepbound)