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In the new categorization of NOD as a high-risk group for PDAC, individuals with NOD stemming from PDAC-associated diabetes rather than other types of diabetes become particularly interesting as diabetes mediated by PDAC has the potential to enable early, non-invasive screening or prompt imaging and invasive diagnostic strategies ( Figure 2 )

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For the mechanism, incidence data, and when it peaks, see our companion explainer on Wegovy and Ozempic (semaglutide) constipation