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Additionally, other research supports its capacity to enhance antioxidant enzyme activity and mitigate oxidative stress in tissues (Yamada et al ., 2018)

RNA isolation, RT-qPCR and RNA-seq analysis Total RNA was extracted from fresh tissues using the Axygen RNA Extraction Kit (Axygen, USA) following the manufacturers instructions

The results demonstrated a substantial decrease in BACE1 levels without any kind of neurotoxicity, thus presenting an alternative for optimal siRNA delivery in gene therapy for AD