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The incorporation of amyloid-related therapy either as an add-on or as a link to specific aspects of AD pathophysiology might become an important trend in clinical trials of new drugs in the future

If short-term use is intended, a provider should design a gradual tapering strategy and post-discontinuation follow-up protocol

Protection of hippocampal neurons from ischemia-induced delayed neuronal death by hepatocyte growth factor: a novel neurotrophic factor

Based on trial eligibility, retatrutide is being investigated in adults who broadly meet the following criteria: BMI of 30 kg/m or above (classified as obese), or BMI of 27 kg/m or above with at least one weight-related comorbidity, such as type 2 diabetes, hypertension, or dyslipidaemia Adults who have not achieved adequate weight loss through lifestyle interventions alone Retatrutide trials to date have enrolled adults only