The active ingredient, semaglutide, is the same molecule found in Ozempic and Wegovy injections, just packaged as a tablet you swallow once a day instead of a once-weekly shot
Compared with WT littermate F10 f/f mice, male and female F10 f/f Villin Cre mice showed unaltered postprandial GIP and GLP-1 levels (Figure 1, N and O), as well as IEC transcript levels of Gip and Glp1 and the upstream transcription factors Rfx6 and Pdx1 (Supplemental Figure 3G)
Used it for a month in morning and evening after facewash
Semaglutide is contraindicated in patients with: Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Common Adverse Effects According to clinical trial data, gastrointestinal effects are most frequently reported: nausea, vomiting, diarrhea, constipation, and abdominal discomfort