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investigated the absorption, metabolism, and excretion of a single 0.5 mg/450 Ci [16.7 MBq] subcutaneous dose of [3 H]-radiolabelled semaglutide in healthy human subjects and compared the results with data from nonclinical studies [56]

503A compounding pharmacies should examine current production trends and formulation trends, including semaglutide or tirzepatide combinations with added APIs, and assess whether monthly volumes remain within any enforcement safe harbor or instead suggest routine commercial substitution

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