Diet & Insulin Resistance Dairy, sugar, and processed foods spike insulin, leading to increased androgen production
demonstrated that CNS leptin administration normalized myocardial fatty acid oxidation, and improved glucose oxidation and mitochondrial function in hearts of leptin-deficient ob/ob mice, and this effect was independent of caloric intake and reduction in body weight [24]
The most common side effects of metformin include: Asthenia (weakness) Diarrhea Nausea/Vomiting Flatulence (passing gas) Discoloration (yellowing) of the fingernails or toenails Constipation Headache Indigestion Heartburn Metallic taste Metformin may also cause a vitamin B12 deficiency over time because it potentially interferes with the absorption of this vitamin
Vandeputte, C., Guizon, I., Genestie-Denis, I., Vannier, B