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doi: 10.3389/ffunb.2025.1742455 Received 09 November 2025 Revised 01 December 2025 Accepted 02 December 2025 Published 18 December 2025 Volume 6 - 2025 Edited by Samantha Chandranath Karunarathna, Qujing Normal University, China Reviewed by Akruti Singh, University of Petroleum and Energy Studies, India Updates Copyright 2025 Wang, Wang and Meade

The company noted the candidate's competitive safety profile and sustained efficacy over 28 weeks, with plans to advance it into Phase 3 trials in 2026

Importantly, any unexpected vaginal bleeding should prompt a pregnancy test in women of reproductive potential, as this is a crucial first step in evaluation

On the other hand, Sermorelin and Tesamorelin are Growth Hormone-Releasing Hormone (GHRH) analogs